Front microrheology of biological fluids

C. Trejo-Soto, E. Costa-Miracle, I. Rodriguez-Villarreal, J. Cid, M. Castro, T. Alarcón, A. Hernández-Machado

20th Chilean Physics Symposium, Santiago de Chile (Chile). 30 November - 02 December 2016

Summary:

We present a study of front microrheology through the development of a microfluidic device and method that describes accurately the non-linear rheology of blood, by means of a simple optical detection method based on tracking the fluid-air interface moving inside a microchannel. We study the behavior of Newtonian fluids of different viscosities and densities, as well, we performed measures for blood at different red blood cells concentration and at different days from its extraction. We have developed a scaling method which allows us to determine a relation between the red blood cell properties at different days from its extraction, according to the agreggation properties of red blood cell. Our results have been compared with theoretical and bibliographical results, which shows realiable results with an error around 6%. In general, our device and method is usefull as a viscometer and rheometer, as well as, it enables to establish a relation between blood viscosity and its red blood cells characteristics.

DOI: https://doi.org/10.1088/1742-6596/1043/1/012058

Published in Journal of Physics: Conference Series, vol: 1043, pp: 012058-1/012058-6, ISSN: 1742-6588

Publication date: 2018-06-25.

Citation:
C. Trejo-Soto, E. Costa-Miracle, I. Rodriguez-Villarreal, J. Cid, M. Castro, T. Alarcón, A. Hernández-Machado, Front microrheology of biological fluids, 20th Chilean Physics Symposium, Santiago de Chile (Chile). 30 November - 02 December 2016. In: Journal of Physics: Conference Series, vol. 1043, ISSN: 1742-6588